Made in Louise, which straddles the Ixelles and Saint Gilles neighborhoods, is a family-run, townhouse-style hotel with 48 suites. The vibe is upscale bed-and-breakfast with cozy yet elegant lodgings and an emphasis on guest experience.
Consider checking into Pillows Grand Hotel Place Rouppe. The newly-refurbished property is surrounded by neoclassical Belgian architecture and includes 43 rooms that marry classic and contemporary. Try signature dishes like salmon gravlax and Thai coconut soup at the onsite restaurant, The Living.
Treat yourself to an indulgent morning at Maison Renardy, an off-the-beaten-path tearoom in Ixelles. Spend some time on the terrace while sampling their selection of tea, pastries, and house-made jams.
Head to Saint Catherine Street for lunch. Here, you’ll find an unassuming seafood market with locals congregating at tables. Dig into the fresh catch of the day which might include fresh Irish oysters, razor clams, or local mussels.
Reserve in advance at Café des Spores, a mushroom-based restaurant in hip Saint-Gilles. Intimate and casual, it’s known for farm-to-table ingredients, with the star of each plate being some variety of mushroom. Although the menu changes seasonally, expect creations like shiitakes with Jerusalem artichoke mousse and enoki and feta croquettes.
In Brussels, a Belgian waffle is a must. Make your way to The Sister Brussels Café, a wellness-leaning breakfast spot offering vegan waffles, Buddha bowls, gluten-free breakfast sandwiches, and more.
Refuel with a wood-fired, organic Neapolitan pizza at NONA. The restaurant places serious emphasis on sustainability and supporting local farmers. Pair a pie with a glass of organic wine.
Make your way through Grand Place to the vibrant L'Amère à Boire for some local beer. The 40-minute walk will take you through some of the most architecturally striking spots in the city. Don’t leave without trying a Lambic—the funky beverage is fermented through exposure to wild bacteria and yeast and is packed with probiotics.
Finish the trip at Tarzan, a Scandinavian-inspired natural wine bar and restaurant. Choose from a rotating menu of vegetarian-friendly shared plates such as homemade hummus, cucumber gazpacho, and beets with avocado mousse.